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EchoTherm™ IC25 Digital, Programmable, Electronic Chilling/Heating Dry Bath

Your Fully Programmable Personal Bench Top Incubator/Chiller/Freezer

Optional Models:

XT Model: Chilling range expanded to -20°C without sample block. Recommended for holding samples steady at low temperatures without cycling.
XR Model: dual Peltier modules for extra power, faster speeds between temperatures and expanded heating to 110°C without sample block. Strongly recommended for larger loads and for cycling temperatures up and down.

IC25 $1,380.00
IC25XT $1,620.00
IC25XR $1,620.00


  • 5-program memory
  • Energy-efficient Peltier design
  • Digital control to 1°C from -20°C to 110°C without sample block
  • Control at ambient
  • Built-in data logger
  • Count down timer (up to 30 days) with audible alarm and user settable Auto-Off
  • RS232 I/O port for data collection
  • Electronic calibration. Factory set, but user can set to any local standard
  • Small, compact size. Uses very little bench space
  • 12-volt DC operation. External power supply provided
  • 12-month warranty
  • UL, CSA and CE compliant

Applications Include:

  • Unattended restriction digestions or ligations at elevated temperatures then reducing temperature to 4°C automatically to reduce non-specific nuclease digestion of target DNA
  • Automatically stopping reactions by having the unit reduce sample temperature after a specific reaction time
  • Producing denatured probes or single stranded DNA molecules by heating to 90°C to 95°C for a given time and rapidly reducing temperature to 4°C to prevent renaturation
  • Automatic temperature profiles to grow bacteria at 37°C, then increasing temperature to induce events, and then lowering temperature to 4°C to prevent degradation
  • Maintaining 14°C for ligation reactions
  • Enzyme reactions and deactivations
  • Maintaining 17°C for storing oocytes
  • Storing reagents at 4C in 15, 50, 250, and 500ml centrifuge tubes
  • Storing samples at ice bucket temperatures without the mess
  • Incubating samples at 37°C in 96-well assay plates or in aluminum blocks holding 0.2, 0.5 and 1.5 ml centrifuge tubes, vials, and test tubes
  • Storing enzyme or DNA libraries at your workstation
  • Freezing and storing most any sample at your workstation

Product Description:

The completely solid-state EchoTherm™ IC25 Digital, Programmable, Electronic Chilling/Heating Dry Bath is versatile, reliable and easy to use. The IC25 has simple digital controls and a two-line alphanumeric display that is backlit for easy reading. The display shows both the target and actual temperatures. Additionally, it displays the timer and all programming functions.

The chilling/heating surface is a 2.875” (7.3 cm) x 4.375” (11.1 cm) aluminum plate that is very flat for optimal contact with the sample. When unloaded, the plate will go below 0°C in under two minutes. It will heat to 37°C in even less time. Generally, the unloaded surface will decrease temperature at about 3°C/minute. Heating rates on the unloaded plate are usually about 5°C/minute. The blocks sold as accessories range in size and mass depending upon the samples used. The unit can drive a block for 1.5 ml centrifuge tubes from ambient temperature to 4°C in less than 30 minutes. When used with an accessory cover these blocks can be driven below 0°C. Temperature gradients from the center to the edge of any accessory block will be less than 0.5°C at any temperature.

The above graph shows a temperature/time profile that can be stored in memory and recalled instantly to be run at any time. The profile was plotted after the data points were collected in buffer. The buffer was then dumped via the RS232 port to a PC. Five programs of as many as ten steps each can be stored in memory. Each step is a temperature and time. Each program can be set to repeat itself up to 99 times.

Product Specification:

Range -10°C to 100°C (IC25), -20C to 100C (IC25XT), -10C to 110C (IC25XR)(minimum temperature possible is 30°C below ambient without sample block)
Readability 1°C
Accuracy ±1°C
Stability ±1°C
Sensor Type Platinum RTD
Controller Type PID
Uniformity ±0.3°C
Range 00:01 to 30 days
Readability 1 second
Audible Alarm Yes, alarm sounds for 1 minute. Timer counts up until UP or DOWN key is touched
Programs Stored 5
Individual Program Capacity 10 Steps
Program Repeat 1–99 times
Memory Backup Yes, in CMOS
Data Logger:
Sample times 1 sec, 1 min or 5 minutes per data point
Capability 7825 data points
Heater/Chiller Peltier, 50 watts (IC25), 100 watts (IC25XT and IC25XR)
Operating Voltages From 90 to 265 volts AC into universal power supply. 12 VDC output to chiller/heater module.
Power Consumption 50 watts (IC25), 100 watts (IC25XT and IC25XR) maximum
Power Switch Yes
Chilling/Heating Module
Width 6.5” (16.5 cm)
Depth 8.75” (22.23 cm)
Height 3.5” (8.9 cm)
Power Supply
Length 6.5” (16.5 cm)
Height 3.2” (8.1 cm)
Width 2.2” (5.6 cm)
Weight (power supply & chiller/heater module) 8 lbs (3.6 kg)

Accessories Available:

For detailed sample block drawings, click here.
620-5012 Block, aluminum, 40 holes for 0.5 ml centrifuge tubes       $185.00
620-5013 Block, aluminum, 30 holes for 1.5 ml centrifuge tubes   $200.00
620-5014 Block, aluminum, 40 holes for 0.5 ml and 15 holes for 1.5 ml   $250.00
620-5015 Block, aluminum, 0.2 ml tubes and plates   $270.00
620-5016 Block, aluminum, “V” bottom 96-well assay plates   $280.00
620-5017 Block, aluminum, round bottom 96-well assay plates   $280.00
620-5018 Block, aluminum, 24 holes for 2.0 ml vials   $205.00
620-5019 Block, aluminum, 384 holes for 384-well assay plates   $280.00
620-5020 Block, aluminum, flat bottom 96 and 384-well assay plates   $210.00
620-5021 Block, aluminum, 24 holes for 10 mm test tubes   $160.00
620-5022 Block, aluminum, 12 holes for 15/16 mm test tubes   $175.00
620-5023 Block, aluminum, 20 holes for 12/13 mm test tubes   $180.00
620-5024 Block, aluminum, 3-20 mm, 5-12/13 mm and 6-6 mm test tubes   $200.00
620-5025 Block, aluminum, 8 holes for 20 mm test tubes   $200.00
620-5026 Block, aluminum, 30 holes for 6 mm test tubes   $180.00
620-5027 Block, aluminum, 12 holes for 15ml centrifuge tubes   $315.00
620-5027I insulation for 620-5027 above.   $80.00
620-5028 Block, aluminum, 12 holes for 20ml scintillation vials   $325.00
620-5029 Block, aluminum, deep-well assay plates   $395.00
620-5030 Block, aluminum, 6 holes for 50ml centrifuge tubes   $295.00
620-5030I Insulation for block 620-5030   $80.00
620-5031 Block, aluminum, 4-slides for hybridizations, with black cover   $380.00
620-5032 Block, aluminum, 30-2.0ml Eppendorf centrifuge tubes   $205.00
620-5033 Block, aluminum, lo-profile, deep-well plates for robots   $280.00
620-5035 Block, Aluminum, lo-profile flat assay plates, for robots   $255.00
620-5036 Block, aluminum, for Nunc 278752 deep well plates. No dealer discount available.   $480.00
620-5041 Block, aluminum, for PCR plates with cones   $265.00
620-5042 Block, aluminum, for Tecan assay plates   $255.00
620-5043 Block, aluminum, for 1.5 ml tubes with slots for caps   $430.00
620-5044 Block, aluminum, 5 V-shaped trough for Tecan   $475.00
620-5045 Block, aluminum, for 2.0 ml tubes with slots for holding caps open for Tecan   $430.00
620-5227, Block, Aluminum, deep well plate, Thermo #95040450. Special order takes 3 weeks. No dealer discount available.   $600.00
620-5254, Block, aluminum, deep well plate, 1.0 ml Greiner Bio 1. Special order takes 3 weeks. No dealer discount available.   $535.00
620-5255 Block, aluminum, deep well plate, Abgene 1.2 ml. Special order takes 3 weeks. No dealer discount available.   $535.00
620-5261 Block, aluminum for one 250ml centrifuge tube. Special order 3 weeks. No distributor discount available   $425.00
620-5261I Insulation for block 620-5261 above.   $80.00
620-5269 Block, aluminum, deep well plate, Phenix 1.1 ml. Special order takes 3 weeks. No dealer discount available.   $635.00
620-5288 Block, aluminum for one 500ml centrifuge tube. Special order takes 3 weeks. No distributor discount available.   $425.00
620-5288I Insulation for block 620-5288 above   $80.00
620-5345 Block, aluminum for two 250ml centrifuge tubes. Special order takes 3 weeks. No distributor discount available.   $425.00
620-5245I Insulation for block 620-5245 above   $80.00
720-0009 Cover, aluminum blocks, 3.25” high   $68.00